Hot-flash relief
Estradiol can help ease moderate to severe menopausal hot flashes.
Night-sweat relief
May help ease moderate to severe night sweats caused by menopause.
Your prescribed routine
Used on the schedule your provider prescribes.
Estradiol can help ease moderate to severe menopausal hot flashes.
May help ease moderate to severe night sweats caused by menopause.
Used on the schedule your provider prescribes.
86% fewer hot flashes
Half the women had at least 86% fewer moderate to severe hot flashes after four weeks on estradiol.*
91%ofwomen
91% of women said they had relief from menopause symptoms after 12 weeks of estradiol with a progestin.**
* Notelovitz et al., Obstetrics & Gynecology (2000). Twelve-week randomized trial, 333 menopausal women across four doses and placebo. The card gives the week-four median reduction for oral micronized estradiol 1 mg, not the percentage of women helped or a guaranteed time to relief. Your prescribed product and strength may differ. Study dose is not an instruction for use. Comparison for the 86% fewer result: Half the women taking oral estradiol 1 mg had at least an 86% drop in moderate to severe hot flashes at week four. On placebo, half had at least a 52% drop. This oral estradiol study measured how much those episodes decreased, with different results at different doses.
** For 91%: Rovati et al., 1999, German trial of 262 women. The 50 mcg/day matrix patch arm included 133 women and cyclic medroxyprogesterone acetate. Its symptom-relief rate was 91%; the comparator reservoir-patch regimen reported 96%. Original study.
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